Sm-a-actin

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August undefined, 2024

WebbActin (Smooth Muscle) (Concentrate) Clone 1A4. This antibody labels smooth muscle cells, myofibroblasts and myoepithelial cells. It is a useful aid for classification of leiomyomas, … Webb24 juni 2024 · Actin is a 43000 kDa ubiquitous protein found in all cells Actins are involved in cell motility (alpha, smooth muscle) and the maintenance of the cytoskeleton (beta and gamma, all cells) Antibodies …

Anti-Alpha-Smooth Muscle Actin Antibodies Invitrogen

WebbThe smooth muscle α-actin and γ-actin proteins are found primarily in vascular smooth muscle and enteric smooth muscle, respectively. The α-smooth muscle actin (ACTA2) is … WebbStress may directly activate transcription of the α-SM actin gene, since application of force across integrin binding sites has been shown to up-regulate α-SM actin promoter activity. 52 As mentioned above, mechanical force alone is not generally sufficient to induce myofibroblast differentiation and other factors are needed to act in concert, specifically … fmla baltimore county

ACTB actin beta [Homo sapiens (human)] - Gene - NCBI

Webbin Sm-a-actin content with increasing age were due, in part, to an increase in Sm-a-actin synthesis. However, in SMCs from 90- and 180-day-old rats, the fractional content of Sm-a-actin exceeded its fractional synthesis at a time when total Sm-a-actin content was increas- ing. This suggests that Sm-a-actin turns over more slowly in mature animals. Webb30 maj 2024 · Western blot results showed that the expression of SM-a-actin and SM-22a was increased, whereas the expression of MMP-2 and TNF-α was decreased in VSMCs treated with 3-MA, in relative to shear stress group (Fig. 4), suggesting that the induction of autophagy could partially block the phenotypic transition of VSMCs. Webb1 mars 2003 · We hypothesized that ablation of smooth muscle α-actin (SM α-A), a contractile-cytoskeletal protein expressed in airway smooth muscle (ASM) cells, … green seal technologies

ACTA2 Gene - GeneCards ACTA Protein ACTA Antibody

WebbThe cell extracts were analyzed by Western blotting with antibodies against SM-a-actin, SRF, Smad2, Smad4, or b-actin as indicated. (B) Serumstarved human lung fibroblasts … Webbα-Smooth Muscle Actin Antibody. #14968. 使用 α-Smooth Muscle Actin Antibody （上）与 GAPDH (D16H11) XP ® Rabbit mAb #5174 （下）对多个组织的提取物进行蛋白质 … greenseam board of governorsWebb21 mars 2024 · GeneCards Summary for ACTA2 Gene. ACTA2 (Actin Alpha 2, Smooth Muscle) is a Protein Coding gene. Diseases associated with ACTA2 include Multisystemic Smooth Muscle Dysfunction Syndrome and Aortic Aneurysm, Familial Thoracic 6 . Among its related pathways are Actin Nucleation by ARP-WASP Complex and Integrin Pathway . fmla california 2022 apply

"Webbof SM a-actin expression involves a complex interaction of multiple positive and negative cis elements that act in a cell-type specific fashion.10–16 For example, a 547 bp SM a-actin promoter/CAT construct (p547CAT) had high activ-ity in cultured SMCs and in L6 skeletal myotubes, which are cell types that express SM a-actin in culture ... " - Sm-a-actin

Sm-a-actin

Transforming growth factor (TGF)-b-induced expression of

Webb11 apr. 2024 · ACT, Acceptance and Commitment Therapy, är en vidareutveckling av Kognitiv Beteendeterapi (KBT). Metoden går ut på att lära sig att acceptera smärtan och … Webb9 maj 2012 · SM-α actin是平滑肌细胞抗体 Actin即“肌动蛋白”，是细胞的一种重要骨架蛋白。同时Actin在细胞分泌、吞噬、 β-Actin 移动、胞质流动和胞质分离等过程中起重要作 …

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WebbSM a-actin promoter is regulated through combinatorial interactions between different factors. Transforming growth factor-b induced activity of the 125-bp rat SM a-actin promoter is dependent on both an intact transforming growth factor-bcontrol element and intact CArG boxes.18 Addition-ally, the homeodomain factor MHox activates SM a-actin Webbalpha-Smooth muscle (alpha-sm) actin, an isoform typical of smooth muscle cells (SMC) and present in high amounts in vascular SMC, was demonstrated in the cytoplasm of …

WebbSmooth muscle alpha-actin (αSMA) is the definitive marker for the activated cardiac fibroblast population known as the myofibroblast (Frangogiannis et al., 2000), but this … WebbSmooth Muscle Actin ( Figures 25-3, A, and 25-4, A) The smooth muscle actin (SMA) marker has a relatively long track record of use as a myoepithelial marker in breast …

Webbα-Actinin 属于细胞骨架蛋白的血影蛋白家族。它最早被确认为肌动蛋白交联蛋白，在每个单体的氨基末端与肌动蛋白结合头形成反向平行同型二聚体。 α-actinin 可以与大量参与 … Webb5 juni 1999 · In this study, the presence of a contractile actin isoform, alpha-smooth muscle (alpha-SM) actin, was assessed by immunohistochemistry in normal calf meniscal tissue and in meniscal cells in 2- and 3-dimensional culture. Calf meniscus cells were seeded in type I and type II collagen-glycosaminoglycan (GAG) matrices.

WebbTransforming growth factor (TGF)-b-induced expression of smooth muscle (SM)-a-actin is accompanied by expression and activation of serum response factor (SRF). (A) Human …

WebbSMC-specific marker genes including SM a-actin, SM myosin heavy chain, SM22, h-caldesmon, calponin, and telokin. The CArGs within any given SMC-specific promoter are … green seam concordiaWebba decrease in expression of SM-a-actin and increases in non-muscle b-actin expression (5). It is presumed that modulation of VSMC phenotype is me-diated through activation of specific signal transduction path-ways that act on transcription factors. In cultured VSMC, increases in SM-a-actin expression are observed in response to specific agonists. fmla center fmlasourceWebb7 okt. 2024 · At E16.5, the expression of SM α-actin cannot detect in both control group and L-NAME treated group (Data not shown). At E17.5, SM α-actin expression observed in large vessels, as well as within ... greenseal window washing productsWebbPulmonary lymphangioleiomyomatosis (LAM) is a rare genetic disease characterized by neoplastic growth of atypical smooth muscle-like LAM cells, destruction of lung parenchyma, obstruction of... fmla case study examplesWebbimmunocytochemical analysis using antibodies specific for either SM a-actin (Skalli et al., 1986) or SM myosin heavy chain (Kawamoto and Adelstein, 1987). Microscopic evaluation of a number of fields failed to uncover SM a-actin- or SM myosin heavy chain-negative cells (data not shown). Additionally, the expression of SM a-actin in fmla certification health care providerWebbwith the Rho kinase inhibitor Y-27632 (10 mM) or actin polymerization with latrunculin B (0.5 mM) significantly decreased the activity of SM22 and SM a-actin promot-ers. In contrast, increasing actin polymerization with jasplakinolide (0.5 mM) increased SM22 and SM a-actin promoter activity by 22-fold and 13-fold, respectively. green seal two dollar billWebb1 jan. 2008 · Alpha-smooth muscle actin (alpha-SMA) is the actin isoform that predominates within vascular smooth-muscle cells and plays an … greenseam celebration of ag