Phospho-acss2
WebJul 7, 2024 · Acetyl-CoA synthetase 2 (ACSS2) is a crucial member of the acetyl-CoA synthetase (ACSS) family and is transcribed from the ACSS2 gene. The ACSS2 gene, first isolated from yeast cells, encodes two isoforms produced by alternative transcription start site selection, with lengths of 1606 bp and 2106 bp [ 8 ]. WebJan 21, 2024 · We interrogate whether ACSS2 can facilitate the local transfer of acetyl groups. Our results point to direct transfer of intact acetate that is mediated by ACSS2, underscoring a critical function of acetate transfer in using local and nuclear acetate pools for histone acetylation and rapid transcriptional activation.
Phospho-acss2
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WebPhospho (6) Supplier US Biological (50) Biorbyt (48) LSBio (39) Aviva Systems Biology (12) antibodies-online (12) ABclonal (2) Abbexa (9) Abbkine (1) Abcam (5) Abgent (2) ... Anti-ACSS2 antibody produced in rabbit. HPA004141 is a primary antibody from MilliporeSigma. 3 Citations Host: Rabbit Clonality: Polyclonal Validations: None Available WebMay 31, 2024 · ACSS2 seems to bind to the promoters of immediate early genes before memory consolidation, implying that acetate, rather than ACSS2, is the limiting factor for histone acetylation at these genes.
WebNov 12, 2024 · ACSS2 is the only known enzyme that can recycle acetate derived from deacetylation reactions in the cytoplasm and nucleus of cells, including both protein and metabolite deacetylation reactions. As such, ACSS2 can recycle acetate derived from histone deacetylase reactions as well as protein deacetylation reactions mediated by … WebDownload scientific diagram Targeting OGT or CDKs blocks GBM growth ex vivo a Representative images depicting tumor growth in organotypic brain slices derived from mice intracranially injected ...
WebThis gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl - …
WebMar 1, 2024 · The standard compounds, including pyruvate, lactate, alanine, acetate, succinate, glucose, palmitate, glycine, glutamate, isoleucine, valine, leucine, and …
WebSep 18, 2024 · Acetyl-CoA synthetase 2 (ACSS2) is a conserved nucleocytosolic enzyme that converts acetate to acetyl-CoA. Adult mice lacking ACSS2 appear phenotypically normal but exhibit reduced tumor burdens in mouse models of liver cancer. The normal physiological functions of this alternate pathway of acetyl-CoA synthesis remain unclear, … fix shapefile encodingWebHome > Protein > ACSS2 New Protein Search: Acetyl-coenzyme A synthetase, cytoplasmic Show on y-axis -References (HTP + LTP) References (LTP) References (HTP) log2 … cannes film festival gewinnerWebMay 25, 2024 · In the nucleus, ACSS2 binds to transcription factor EB and translocates to lysosomal and autophagy gene promoter regions, where ACSS2 incorporates acetate generated from histone acetylation turnover to locally produce acetyl-CoA for histone H3 acetylation in these regions and promote lysosomal biogenesis, autophagy, cell survival, … cannes film festival horrorWebJun 1, 2024 · ACSS2 is phosphorylated at Ser659 by AMPK and then forms a translocation complex with Importin α5 to translocate into the nucleus. This process interacts with TFEB, resulting in upregulated... fix shape of cushion foamWebACSS2 / ACAS2 is a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate ... cannes film awardWebMar 8, 2024 · Influenza virus is responsible for respiratory diseases that can be severe or even lethal, especially in young children and the elderly 1.The virus causes annual … f.i.x shapewear by underwearWeb(orb1096966) ACSS2 (Phospho-Ser659) Antibody Sign in or register to save this reagent to your favourites Supplier Biorbyt Host Rabbit Type Primary Clonality Polyclonal Conjugate Unconjugated Modification Phospho (Ser659) View Product On Supplier's Website Request a Quote from Biorbyt Supplier provided information Validations None provided fix shapewear