Lineage specifiers

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August undefined, 2024

Nettet3. okt. 2013 · Recent studies show that lineage specifiers play an important role in orchestrating the process of restoring pluripotency by replacing pluripotency-associated … Nettet23. mai 2013 · Here, we identified eight lineage specifiers as OCT4 substitutes, including GATA3, GATA6, and SOX7, which are involved in mesendodermal (ME) lineage …

A computational strategy for predicting lineage specifiers …

Nettet23. mai 2013 · Here, we report that, during mouse somatic cell reprogramming, pluripotency can be induced with lineage specifiers that are pluripotency rivals to … Nettet18. jul. 2013 · Upon differentiation, pluripotent marker expression is downregulated alongside unrelated lineage specifiers. Downregulation of certain lineage specifiers … dry spanish

Lineage specifiers: new players in the induction of pluripotency

NettetLocate the My Games section on the right hand side and click the LINEAGE II option. Click the Apply In-Game Items link. Select the server that is home to the character you wish … Nettet4. okt. 2013 · Lastly, the lineage specifiers depicted as pluripotency rivals, such as GATA3 and PAX6, have been identified to be able to restore pluripotency in somatic cells. Based on these discoveries, we should reconsider the definitions of pluripotency and lineage specification and present a novel perspective for understanding the … NettetLineage W. Lineage W is a massively multiplayer online role-playing game (MMORPG) developed and published by NCSoft. It is a fifth major installment of the Lineage series … commenting toolbar

Computational Methods to Identify Cell-Fate Determinants

A single-cell transcriptome atlas of marsupial embryogenesis and …

NettetScreening of Other Lineage Specifiers as Substitutes for OCT4 The current model proposes that ESCs are maintained by a shield of pluripotency factors that collaboratively prohibit differentiation into any lineage to preserve an undifferentiated state ( … Nettet23. mai 2013 · Induction of Pluripotency in Mouse Somatic Cells with Lineage Specifiers. Previous Article Integrative Clinical Genomics of Advanced Prostate Cancer. Next Article Cytotoxic Cells Kill Intracellular Bacteria through Granulysin-Mediated Delivery of Granzymes (Cell 153, 963–975, May 23, 2013) dry sparknotesNettetHNF4α also directly represses SIX4 and SIX1, two mesodermal/neuronal lineage specifiers expressed in the basal-like subtype. Finally, SIX4 and SIX1 drive proliferation and regulate ... dry spaghetti to cooked ratio

"Nettet5. sep. 2013 · Our results show that it is possible to replace OCT4 and SOX2 simultaneously with alternative lineage specifiers in the reprogramming of human cells. … " - Lineage specifiers

Lineage specifiers

NettetHere, we identified eight lineage specifiers as OCT4 substitutes, including GATA3, GATA6, and SOX7, which are involved in mesendodermal (ME) lineage specification. … Nettet23. mai 2013 · Induction of Pluripotency in Mouse Somatic Cells with Lineage Specifiers. Previous Article Integrative Clinical Genomics of Advanced Prostate Cancer. Next …

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NettetSurprisingly, the two counteracting lineage specifiers can synergistically induce pluripotency in the absence of both OCT4 and SOX2. Our study suggests a "seesaw model" in which a balance that is established using pluripotency factors and/or counteracting lineage specifiers can facilitate reprogramming. Nettet21. mai 2015 · Traditionally, the overexpression of lineage specifiers counteracts pluripotency networks (Loh and Lim, 2011). In recent years, several lineage specifiers …

NettetRecent studies show that lineage specifiers play an important role in orchestrating the process of restoring pluripotency by replacing pluripotency-associated transcription factors. Nettet8. mai 2024 · This Game could be to some extent analogous to a mouse blastomere with undecided fate, where lineage specifiers with opposing effects co-exist inside the blastomere along with other regulatory...

Nettet12. nov. 2015 · Schematic view of the proposed method for predicting lineage specifiers of stem cell differentiation using single-cell gene expression data. Candidate lineage …

NettetRecently, lineage specifiers have been identified to play important roles in orchestrating the process of restoring pluripotency. In this review, we summarize the latest …

Nettet1. sep. 2015 · Candidate lineage specifiers are identified in three steps. First, a transcriptional regulatory network (TRN) is inferred using single-cell gene expression data, literature knowledge and transcription factor (TF)-DNA binding-site prediction. dry speakingNettet23. mai 2013 · An alternative explanation is that lineage specifiers execute their role in pluripotency induction regardless of their main activity in lineage specification yet not through activation of pluripotency genes ( Figure 1 B, II). dr y.s parmar university solanNettet17. feb. 2024 · Precisely, the lineage specifiers were predicted for inner cell mass (ICM), hematopoietic stem cells (HSC), multipotent progenitor (MPP), common myeloid progenitor (CMP), and lung alveolar bipotential progenitor (BP) differentiations. commenting vbaNettet13. sep. 2016 · The Method Predicted Known Lineage Specifiers Even when Differentiation Is Incomplete. The method was also applied to the dataset of CPC differentiation, in which hESCs were differentiated into MESP1 + and MESP1 − (pre-)CPCs (den Hartogh et al., 2015), where only the former was able to differentiate further into … dry spanish riceNettet28. mai 2013 · Background Ethanol is a toxin responsible for the neurodevelopmental deficits of Fetal Alcohol Spectrum Disorders (FASD). Recent evidence suggests that ethanol modulates the protein expression of lineage specifier transcription factors Oct4 (Pou5f1) and Sox2 in early stages of mouse embryonic stem (ES) cell differentiation. … dry spaghetti sauce seasoning mix recipeNettetChoosing your character’s race and class is one of the most special and shaping events you will experience as you begin to play Lineage II. Your character will be what you … dry spackle add waterNettet8. apr. 2011 · In our model, the expression of a myriad of diverse lineage specifiers within ESCs provides them with all the developmental … dry spell during pregnancy